Previous work carried out to characterise different immune cells in ruminant placentas found strong CD79αcy nuclear labelling in cells histologically resembling trophoblast cells. In the attempt to characterize this cell population, placentomes collected from cattle, sheep and water buffaloes were examined by immunohistochemistry with single and double labelling using monoclonal antibodies (mAb) against B lymphocytes and trophoblast cells. Most CD79αcy + cells co-expressed placental lactogen or cytokeratin and were CD21 and MHC class II negative strongly suggesting they do not have a B cell origin. However, a potential immunological role of these cells cannot be ruled out and it is currently unknown if the findings described may have an impact on physiological knowledge, health, and or diseases pathogenesis in ruminants.

中文翻译：

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反刍动物胎盘中CD79αcy+细胞的表征。

为表征反刍动物胎盘中的不同免疫细胞而进行的先前工作发现，在组织学上类似于滋养层细胞的细胞中，CD79αcy核标记很强。为了表征该细胞群，使用针对B淋巴细胞和滋养层细胞的单克隆抗体（mAb），通过免疫组化对带有牛，羊和水牛的胎盘进行了单组和双组标记的免疫组织化学检查。大多数CD79αcy+细胞共表达胎盘泌乳素或细胞角蛋白，并且CD21和MHC II类阴性，强烈表明它们没有B细胞起源。但是，不能排除这些细胞的潜在免疫学作用，目前尚不清楚所描述的发现是否可能对反刍动物的生理知识，健康和/或疾病发病机理产生影响。