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Allelic variant in CTLA4 is associated with thyroid failure and faster β-cell exhaustion in latent autoimmune diabetes in adults.
Journal of Diabetes ( IF 3.0 ) Pub Date : 2014-03-27 , DOI: 10.1111/1753-0407.12137
Alessandro P. Delitala 1 , Giuseppe Fanciulli 2 , Magdalena Zoledziewska 3, 4 , Maristella Pitzalis 3, 4 , Pierpaolo Pusceddu 5 , Paola Frongia 5 , Loreta Puddu 2 , Alessandra Errigo 2 , Margherita Maioli 1 , Giuseppe Delitala 2 , Giovanni M. Pes 2
Affiliation  

The aim of the study was to investigate the role of the cytotoxic T‐lymphocyte‐associated protein 4 (CTLA4) G6230A variant on the susceptibility of latent autoimmune diabetes in adults (LADA) as a whole and in the subset of patients who share autoimmune thyroid disease (AITD).

中文翻译:

成人潜在的自身免疫性糖尿病中,CTLA4的等位基因变异与甲状腺功能衰竭和更快的β细胞衰竭有关。

这项研究的目的是研究细胞毒性T淋巴细胞相关蛋白4(CTLA4)G6230A变体在成年人(LADA)和患有自身免疫性甲状腺疾病的患者亚组中对潜伏性自身免疫性糖尿病易感性的作用疾病(AITD)。
更新日期:2014-03-27
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