The effects of hypergravity stress on L-[14C]-glutamate release from synaptosomes obtained from the rat brain and on the kinetic parameters of high-affinity glutamate transport activity were investigated. We found that hypergravity stress affected only the Ca(2+)-dependent component of L-[14C]-glutamate release. It did not modify the transporter affinity, but the maximum rate of uptake dropped from 12.5 +/- 3.2 to 5.6 +/- 0.9 nmol/min/mg of protein (in control rats and in animals subjected to hypergravity, respectively).

中文翻译：

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谷氨酸能在大鼠大脑中的传播和重力应激。

研究了超重力胁迫对大鼠脑突触体释放L- [14C]-谷氨酸的影响以及对高亲和力谷氨酸转运活性动力学参数的影响。我们发现超重力应力仅影响L- [14C]-谷氨酸释放的Ca（2+）依赖组件。它没有改变转运蛋白的亲和力，但是最大摄取速率从12.5 +/- 3.2 nmol / min / mg蛋白质降低了（分别在对照大鼠和超重力动物中）。