Weight-associated stigmatization and discrimination may induce chronic stress in individuals with obesity. As a consequence, this stressor may cause an imbalance of HPA stress axis leading to increased eating behavior, and ultimately, weight gain. However, the direct link between internalized weight bias and stress response to acute stressors via cortisol secretion has not been investigated so far. Therefore, the purpose of this study was to investigate the interaction between internalized weight stigma as a stressor and cortisol reactivity in an acute psychosocial stress situation induced by the Trier Socials Stress Test for groups (TSST-G). Participants with BMI >30 kg/m2 (n = 79) were included in the study. Results reveal that while individuals with low internalized stigma reacted as predicted with an increase in cortisol secretion to acute psychosocial stress, individuals with medium or high internalized stigma did not show a typical cortisol response. However, these findings depend on the several factors, for instance on gender. In sum, acute stress in individuals with internalized weight bias seems to blunt HPA axis reactions to acute psychosocial stress. The study contributes to the understanding of the psychological and endocrinological consequences of internalized weight bias and underlines the importance of interventions to reduce stigmatization.

中文翻译：

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内在的体重偏差和皮质醇对社会压力的反应。

体重相关的污名化和歧视可能会导致肥胖个体的慢性压力。结果，这种压力源可能导致HPA压力轴失衡，从而导致进食行为增加，最终导致体重增加。然而，到目前为止，尚未研究内在化的体重偏差与通过皮质醇分泌对急性应激源的应激反应之间的直接联系。因此，本研究的目的是研究在特里尔社会压力测试（TSST-G）引起的急性社会心理压力情况下，作为压力源的负重柱头与皮质醇反应性之间的相互作用。BMI> 30 kg / m2（n = 79）的参与者被纳入研究。结果表明，尽管具有低内在化的柱头的个体反应如所预期的那样，对急性社会心理压力的皮质醇分泌增加，但是具有中或内在的柱头的个体没有显示出典型的皮质醇反应。但是，这些发现取决于几个因素，例如性别。总而言之，内在性偏向的个体的急性应激似乎使HPA轴对急性心理应激的反应变钝。这项研究有助于人们理解内在的体重偏差的心理和内分泌后果，并强调了减少污名化的干预措施的重要性。具有内在的体重偏差的人的急性应激似乎使HPA轴对急性心理应激的反应变钝。这项研究有助于人们理解内在的体重偏差的心理和内分泌后果，并强调了减少污名化的干预措施的重要性。具有内在的体重偏差的人的急性应激似乎使HPA轴对急性心理应激的反应变钝。这项研究有助于人们理解内在的体重偏差的心理和内分泌后果，并强调了减少污名化的干预措施的重要性。