Epithelial organization and function depend on coordinated cell polarity. In developing tissues, proliferative epithelia maintain whole tissue polarity as individual cells undergo symmetric divisions. However, recent work has shown that cells in diverse epithelia remodel their polarity in a cell cycle-dependent manner. Here, we discuss the different mechanisms that drive mitotic polarity oscillations and their implications for tissue morphogenesis.

中文翻译：

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有丝分裂上皮细胞的极性振荡。

上皮组织和功能取决于协调的细胞极性。在发育中的组织中，随着单个细胞进行对称分裂，增殖上皮维持整个组织的极性。然而，最近的研究表明，多种上皮细胞以细胞周期依赖性方式重塑其极性。在这里，我们讨论驱动有丝分裂极性振荡的不同机制及其对组织形态发生的影响。