There is growing evidence for neuropsychological dysfunction in obsessive-compulsive disorder (OCD) related to an underlying frontal lobe and/or basal ganglia dysfunction. The following paper is a systematical review of the existing literature on cognitive impairment in OCD patients. Fifty studies were surveyed with regard to methodological aspects and cognitive impairments found in OCD patients. In addition, the impact of confounding variables such as psychotropic medication, co-morbidity or severity of symptoms on neuropsychological functioning as well as effects of treatment are discussed. OCD is often related to memory dysfunction that seems to be associated with impaired organization of information at the stage of encoding. Several other executive functions are also commonly disturbed, though results are inconsistent. The results of our study suggest that some cognitive deficits seem to be common in OCD, but future studies should focus more on possible confounding variables such as co-morbidity or psychotropic medication.

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强迫症的神经心理学表现：批判性评论

越来越多的证据表明，与潜在额叶和/或基底神经节功能障碍相关的强迫症 (OCD) 中的神经心理功能障碍。以下论文是对现有关于强迫症患者认知障碍的文献的系统回顾。对 50 项研究进行了有关方法学方面和在强迫症患者中发现的认知障碍的调查。此外，还讨论了诸如精神药物、合并症或症状严重程度等混杂变量对神经心理功能以及治疗效果的影响。强迫症通常与记忆功能障碍有关，这似乎与编码阶段的信息组织受损有关。其他几种执行功能也普遍受到干扰，但结果并不一致。