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Perinatal variation and covariation of oxidative status and telomere length in yellow-legged gull chicks
Current Zoology ( IF 2.2 ) Pub Date : 2018-11-14 , DOI: 10.1093/cz/zoy084
Marco Parolini 1 , Cristina Daniela Possenti 1 , Andrea Romano 1, 2 , Manuela Caprioli 1 , Diego Rubolini 1 , Nicola Saino 1
Affiliation  

Abstract The perinatal period is critical to survival and performance of many organisms. In birds, rapid postnatal growth and sudden exposure to aerial oxygen around hatching markedly affect the chick redox status, with potentially negative consequences on physiology mediated by oxidative stress. In addition, telomere length (TL) undergoes reduction during birds’ early life, partly depending on oxidative status. However, relatively few studies have focused specifically on the changes in oxidative status and TL that occur immediately after hatching. In this study of the yellow-legged gull Larus michahellis, we found that chicks undergo a marked increase in plasma total antioxidant capacity and a marked decrease in the concentration of pro-oxidant molecules during the first days after hatching. In addition, TL in erythrocytes decreased by 1 standard deviation over the 4 days post-hatching. Body mass and tarsus length covaried with total antioxidant capacity and concentration of pro-oxidants in a complex way, that partly depended on sex and laying order, suggesting that oxidative status can affect growth. Moreover, TL positively covaried with the concentration of pro-oxidant molecules, possibly because retention of high concentrations of pro-oxidant molecules results from mechanisms of prevention of their negative effects, including reduction in TL. Thus, this study shows that chicks undergo marked variation in oxidative status, which predicts growth and subsequent TL, prompting for more studies of the perinatal changes in the critical post-hatching stages.

中文翻译:

黄腿鸥雏鸟氧化状态和端粒长度的围产期变异及协变

摘要 围产期对许多生物的生存和性能至关重要。在鸟类中,出生后的快速生长和孵化周围突然暴露于空气中的氧气会显着影响小鸡的氧化还原状态,对氧化应激介导的生理机能产生潜在的负面影响。此外,端粒长度 (TL) 在鸟类早期生命期间会减少,部分取决于氧化状态。然而,相对较少的研究专门关注孵化后立即发生的氧化状态和 TL 的变化。在这项对黄腿鸥 Larus michahellis 的研究中,我们发现雏鸟在孵化后的最初几天血浆总抗氧化能力显着增加,促氧化分子浓度显着降低。此外,在孵化后 4 天内,红细胞中的 TL 降低了 1 个标准偏差。体重和跗骨长度与总抗氧化能力和促氧化剂浓度以复杂的方式共变,这部分取决于性别和产蛋顺序,这表明氧化状态会影响生长。此外,TL 与促氧化剂分子的浓度呈正相关,这可能是因为高浓度促氧化剂分子的保留是由于防止其负面影响的机制,包括 TL 的减少。因此,这项研究表明,雏鸡的氧化状态会发生显着变化,这可以预测生长和随后的 TL,促使对孵化后关键阶段的围产期变化进行更多研究。体重和跗骨长度与总抗氧化能力和促氧化剂浓度以复杂的方式共变,这部分取决于性别和产蛋顺序,这表明氧化状态会影响生长。此外,TL 与促氧化剂分子的浓度呈正相关,这可能是因为高浓度促氧化剂分子的保留是由于防止其负面影响的机制,包括 TL 的减少。因此,这项研究表明,雏鸡的氧化状态会发生显着变化,这可以预测生长和随后的 TL,促使对孵化后关键阶段的围产期变化进行更多研究。体重和跗骨长度与总抗氧化能力和促氧化剂浓度以复杂的方式共变,这部分取决于性别和产蛋顺序,这表明氧化状态会影响生长。此外,TL 与促氧化剂分子的浓度呈正相关,这可能是因为高浓度促氧化剂分子的保留是由于防止其负面影响的机制,包括 TL 的减少。因此,这项研究表明,雏鸡的氧化状态会发生显着变化,这可以预测生长和随后的 TL,促使对孵化后关键阶段的围产期变化进行更多研究。TL 与促氧化剂分子的浓度呈正共变,可能是因为高浓度促氧化剂分子的保留是由于防止其负面影响的机制,包括减少 TL。因此,这项研究表明,雏鸡的氧化状态会发生显着变化,这可以预测生长和随后的 TL,促使对孵化后关键阶段的围产期变化进行更多研究。TL 与促氧化剂分子的浓度呈正共变,可能是因为高浓度促氧化剂分子的保留是由于防止其负面影响的机制,包括减少 TL。因此,这项研究表明,雏鸡的氧化状态会发生显着变化,这可以预测生长和随后的 TL,促使对孵化后关键阶段的围产期变化进行更多研究。
更新日期:2018-11-14
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