The Zika virus (ZIKV) is an emerging flavivirus transmitted primarily through arthropods, endemic in Africa, Asia, and the Americas, and is considered a global threat by the World Health Organization. OBJECTIVE To evaluate a commercial Zika virus test (IgG/IgM catalog number B815C, Biocan, Canada. METHODS We evaluated 30 sera of patients diagnosed with Dengue, Leptospira, Malaria, Hantavirus, and Chikungunya. To establish the sensitivity of the test, two groups of sera were analyzed, the first one was patients with Zika RT-qPCR positive, and the second were patients RT-qPCR negative but with clinical suspicion of Zika. RESULTS The specificity was of 23.3% (7/30), the sensitivity in acute patients with positive RT-qPCR was of 63.6%, the patients with clinical suspicion of Zika the sensitivity (IgM) was of 80% (n = 8/10). Overall sensitivity (IgM) of both groups was of 71.4% (15/21). CONCLUSIONS The test showed a low specificity to be used as a serological test in an endemic area of flavivirus infection.

中文翻译：

---

在哥伦比亚加勒比地区黄病毒流行区进行的寨卡病毒血清学检测评估。

寨卡病毒（ZIKV）是一种新兴的黄病毒，主要通过节肢动物传播，在非洲，亚洲和美洲是地方性流行病，被世界卫生组织视为全球性威胁。目的评估商业寨卡病毒测试（IgG / IgM，目录号B815C，加拿大Biocan。方法）我们评估了30例诊断为登革热，钩端螺旋体，疟疾，汉坦病毒和基孔肯雅病患者的血清。为确定测试的敏感性，两组结果：特异性为23.3％（7/30），在急性中的敏感性为23.3％（7/30），其中血清为Zika RT-qPCR阳性，其次为RT-qPCR阴性，但临床上怀疑有寨卡。 RT-qPCR阳性的患者为63.6％，临床怀疑寨卡病毒的患者的敏感性（IgM）为80％（n = 8/10）。两组的总敏感性（IgM）为71.4％（15/21）。结论该测试显示在黄病毒感染的流行地区用作血清学测试的特异性较低。