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Sexually transmitted infections and HIV in the era of antiretroviral treatment and prevention: the biologic basis for epidemiologic synergy
Journal of the International AIDS Society ( IF 4.6 ) Pub Date : 2019-08-01 , DOI: 10.1002/jia2.25355
Myron S Cohen 1 , Olivia D Council 2 , Jane S Chen 3
Affiliation  

HIV is a unique sexually transmitted infection (STI) that is greatly affected by other concomitant “classical” bacterial and viral STIs that cause genital ulcers and/or mucosal inflammation. STIs also serve as a marker for risky sexual behaviours. STIs increase infectiousness of people living with HIV by increasing the viral concentration in the genital tract, and by increasing the potential for HIV acquisition in people at risk for HIV. In addition, some STIs can increase blood HIV concentration and promote progression of disease. This review is designed to investigate the complex relationship between HIV and classical STIs.

中文翻译:

抗逆转录病毒治疗和预防时代的性传播感染和艾滋病毒:流行病学协同作用的生物学基础

HIV 是一种独特的性传播感染 (STI),它受到其他伴随的“经典”细菌和病毒性 STI 的影响,这些感染会导致生殖器溃疡和/或粘膜炎症。性传播感染也是危险性行为的标志。性传播感染通过增加生殖道中的病毒浓度以及增加有感染艾滋病毒风险的人感染艾滋病毒的可能性来增加艾滋病毒感染者的传染性。此外,一些性传播感染可以增加血液中艾滋病毒浓度并促进疾病进展。本综述旨在调查艾滋病毒和经典性传播感染之间的复杂关系。
更新日期:2019-08-01
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