The genus Caldicellulosiruptor is comprised of extremely thermophilic, heterotrophic anaerobes that degrade plant biomass using modular, multifunctional enzymes. Prior pangenome analyses determined that this genus is genetically diverse, with the current pangenome remaining open, meaning that new genes are expected with each additional genome sequence added. Given the high biodiversity observed among the genus Caldicellulosiruptor, we have sequenced and added a 14th species, Caldicellulosiruptor changbaiensis, to the pangenome. The pangenome now includes 3791 ortholog clusters, 120 of which are unique to C. changbaiensis and may be involved in plant biomass degradation. Comparisons between C. changbaiensis and Caldicellulosiruptor bescii on the basis of growth kinetics, cellulose solubilization and cell attachment to polysaccharides highlighted physiological differences between the two species which are supported by their respective gene inventories. Most significantly, these comparisons indicated that C. changbaiensis possesses uncommon cellulose attachment mechanisms not observed among the other strongly cellulolytic members of the genus Caldicellulosiruptor.

中文翻译：

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基因组学和生理学分析表明，嗜热的长白Caldicellulosiruptor昌百部署了罕见的纤维素附着机制。

Caldicellulosiruptor属由高度嗜热的异养厌氧菌组成，可利用模块化多功能酶降解植物生物量。先前的全基因组分析确定该属在遗传上是多样的，而当前的全基因组仍处于开放状态，这意味着期望在每个附加的基因组序列中添加新基因。鉴于在Caldicellulosiruptor属中观察到的高度生物多样性，我们已对全基因组进行了测序，并将第14个物种changbaiensis Caldicellulosiruptor changbaiensis添加到了该基因组。泛基因组现在包括3791个直系同源簇，其中120个是长白梭菌独有的，可能参与植物生物量的降解。根据生长动力学比较长白梭菌和贝氏梭状芽孢杆菌之间的比较，纤维素的增溶作用和细胞对多糖的附着突出了两个物种之间的生理差异，这由它们各自的基因清单支持。最重要的是，这些比较表明，长白梭菌具有在Caldicellulosiruptor属的其他强纤维素分解成员中未发现的罕见的纤维素附着机制。