BACKGROUND Intraoperative computed tomography (iCT) system has been developed focusing on combining the advanced imaging techniques for the best imaging modality. However, the use of iCT system in the operating rooms is limited due to the lack of flexible mobility. OBJECTIVE This study aims to develop a mobile iCT imaging system and assess its imaging performance in a phantom study. METHODS The mobile iCT system with mecanum omni-directional wheels has three major components namely, a rotating gantry, a slip-ring and a stationary gantry. Performance of mecanum iCT system was evaluated using the indices of signal-to-noise (SNR), contrast-to noise (CNR), and spatial resolution (MTF). Anatomical landmarks on phantom images were assessed using a 5-point scale (5 = definitely seen; 4 = probably seen; 3 = equivocal; 2 = probably not seen; and 1 = definitely not seen). RESULTS The mecanum iCT system can be conveniently used for a whole-body scan under intraoperative conditions even in narrow operating rooms due to a smaller turning radius. The image quality of the mecanum iCT system was found to be acceptable for clinical applications (with SNR = 162.72, CNR = 134.29 and MTF = 694 μm). The diagnostic scores on the phantom images were 'definitely seen' value. CONCLUSIONS The proposed mecanum iCT system achieved the improved flexible mobility and has potential to better serve as a useful imaging tool in the clinical intraoperative setting.

中文翻译：

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术中移动计算机断层摄影成像系统的开发及其在脑和体模研究中的性能评估。

背景技术已经开发出术中计算机断层摄影（iCT）系统，其重点在于结合先进的成像技术以获得最佳成像方式。但是，由于缺乏灵活的移动性，iCT系统在手术室中的使用受到限制。目的本研究旨在开发一种移动iCT成像系统，并在幻像研究中评估其成像性能。方法带有麦克纳姆全向轮的移动iCT系统具有三个主要组成部分，即旋转机架，滑环和固定机架。使用信噪比（SNR），对比噪声（CNR）和空间分辨率（MTF）的指标评估了麦克纳姆iCT系统的性能。幻像图像上的解剖标志使用5分制进行评估（5 =肯定可见； 4 =可能可见； 3 =模棱两可； 2 =可能看不到；和1 =绝对看不到）。结果麦克纳姆iCT系统由于较小的转弯半径，即使在狭窄的手术室中，也可在术中条件下方便地用于全身扫描。发现麦克纳姆iCT系统的图像质量可用于临床应用（SNR = 162.72，CNR = 134.29和MTF = 694μm）。体模图像上的诊断得分为“绝对可见”值。结论拟议的麦克纳姆iCT系统实现了改善的柔性活动性，并有可能在临床术中更好地用作有用的成像工具。发现麦克纳姆iCT系统的图像质量可用于临床应用（SNR = 162.72，CNR = 134.29，MTF = 694μm）。体模图像上的诊断得分为“绝对可见”值。结论拟议的麦克纳姆iCT系统实现了改善的柔性活动性，并有可能在临床术中更好地用作有用的成像工具。发现麦克纳姆iCT系统的图像质量可用于临床应用（SNR = 162.72，CNR = 134.29，MTF = 694μm）。体模图像上的诊断得分为“绝对可见”值。结论拟议的麦克纳姆iCT系统实现了改善的柔性活动性，并有可能在临床术中更好地用作有用的成像工具。