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Sample sizes and statistical methods in interventional studies on individuals with spinal cord injury: A systematic review.
Journal of Evidence-Based Medicine ( IF 3.6 ) Pub Date : 2019-06-23 , DOI: 10.1111/jebm.12356
Georg Zimmermann 1, 2, 3 , Lisa-Maria Bolter 3 , Ronny Sluka 4 , Yvonne Höller 1 , Arne C Bathke 3 , Aljoscha Thomschewski 1, 2, 4 , Stefan Leis 1 , Simona Lattanzi 5 , Francesco Brigo 6, 7 , Eugen Trinka 1, 8
Affiliation  

Prevalence and incidence of spinal cord injury (SCI) are low. However, sample sizes have not been systematically examined yet, although this might represent useful information for study planning and power considerations. Therefore, our objective was to determine the median sample size in clinical trials on SCI individuals. Moreover, within small‐sample size studies, statistical methods and awareness of potential problems regarding small samples were examined.

中文翻译:

脊髓损伤个体介入研究的样本量和统计方法:系统评价。

脊髓损伤(SCI)的患病率和发生率较低。然而,样本量尚未得到系统检查,尽管这可能代表了对研究计划和功效考虑有用的信息。因此,我们的目标是确定 SCI 个体临床试验中的中位样本量。此外,在小样本量研究中,还检查了统计方法和对小样本潜在问题的认识。
更新日期:2019-06-23
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