Abstract A new phenolic sesquiterpene, dysoxyphenol (1), and the known sesquiterpene, 7R,10S-2-hydroxycalamenene (2), were isolated from the acetone extract of Dysoxylum densiflorum seeds. The structures of these compounds were determined based on physical, Nuclear Magnetic Resonance, and mass spectral data. Both compounds were evaluated for their antibacterial and antifungal properties against seven pathogenic bacteria and two wood-rotting fungi, respectively. The results showed that both compounds have significant antibacterial properties only against Bacillus subtilis (Minimum Inhibitory Concentration 28 μM), while in the antifungal evaluation compound 1 was found to be more active than compound 2. Therefore, compound 1 has promising antifungal properties that can be developed further for finding new antifungal agents.

中文翻译：

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来自 Dysoxylum densiflorum 的抗菌和抗真菌两种酚类倍半萜

摘要 从木香种子的丙酮提取物中分离出一种新的酚类倍半萜，dysoxyphenol (1) 和已知的倍半萜，7R,10S-2-hydroxycalamenene (2)。这些化合物的结构是根据物理、核磁共振和质谱数据确定的。分别评估了这两种化合物对七种病原菌和两种木材腐烂真菌的抗菌和抗真菌特性。结果表明，这两种化合物仅对枯草芽孢杆菌具有显着的抗菌性能（最低抑制浓度 28 μM），而在抗真菌评估中发现化合物 1 比化合物 2 更有效。因此，化合物 1 具有良好的抗真菌特性，可以进一步开发以寻找新的抗真菌剂。