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Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA.
Magnetic Resonance Materials in Physics Biology and Medicine ( IF 2.0 ) Pub Date : 2019-10-18 , DOI: 10.1007/s10334-019-00784-w
Iosif Mendichovszky 1 , Pim Pullens 2 , Ilona Dekkers 3 , Fabio Nery 4 , Octavia Bane 5 , Andreas Pohlmann 6 , Anneloes de Boer 7 , Alexandra Ljimani 8 , Aghogho Odudu 9 , Charlotte Buchanan 10 , Kanishka Sharma 11 , Christoffer Laustsen 12 , Anita Harteveld 7 , Xavier Golay 13 , Ivan Pedrosa 14 , David Alsop 15 , Sean Fain 16 , Anna Caroli 17 , Pottumarthi Prasad 18 , Susan Francis 10 , Eric Sigmund 19 , Maria Fernández-Seara 20 , Steven Sourbron 11
Affiliation  

PURPOSE The potential of renal MRI biomarkers has been increasingly recognised, but clinical translation requires more standardisation. The PARENCHIMA consensus project aims to develop and apply a process for generating technical recommendations on renal MRI. METHODS A task force was formed in July 2018 focused on five methods. A draft process for attaining consensus was distributed publicly for consultation and finalised at an open meeting (Prague, October 2018). Four expert panels completed surveys between October 2018 and March 2019, discussed results and refined the surveys at a face-to-face meeting (Aarhus, March 2019) and completed a second round (May 2019). RESULTS A seven-stage process was defined: (1) formation of expert panels; (2) definition of the context of use; (3) literature review; (4) collection and comparison of MRI protocols; (5) consensus generation by an approximate Delphi method; (6) reporting of results in vendor-neutral and vendor-specific terms; (7) ongoing review and updating. Application of the process resulted in 166 consensus statements. CONCLUSION The process generated meaningful technical recommendations across very different MRI methods, while allowing for improvement and refinement as open issues are resolved. The results are likely to be widely supported by the renal MRI community and thereby promote more harmonisation.

中文翻译:

肾脏 MRI 临床转化的技术建议:PARENCHIMA 科技合作共识项目。

目的 肾脏 MRI 生物标志物的潜力已被越来越多地认可,但临床转化需要更多的标准化。PARENCHIMA 共识项目旨在开发和应用一个产生肾脏 MRI 技术建议的过程。方法 2018 年 7 月成立了一个工作组,重点关注五种方法。达成共识的流程草案已公开分发以供协商,并在一次公开会议上最终确定(布拉格,2018 年 10 月)。四个专家小组在 2018 年 10 月至 2019 年 3 月之间完成了调查,在一次面对面会议(奥胡斯,2019 年 3 月)上讨论了结果并完善了调查,并完成了第二轮调查(2019 年 5 月)。结果 定义了一个七个阶段的过程:(1)专家小组的形成;(2) 使用上下文的定义;(3) 文献综述;(4) MRI协议的收集和比较;(5) 近似德尔菲法的共识生成;(6) 以供应商中立和供应商特定条款报告结果;(7) 持续审查和更新。该过程的应用产生了 166 份共识​​声明。结论 该过程在非常不同的 MRI 方法中产生了有意义的技术建议,同时允许在解决未解决的问题时进行改进和细化。该结果可能会得到肾脏 MRI 社区的广泛支持,从而促进更多的协调。同时允许在解决未解决的问题时进行改进和细化。该结果可能会得到肾脏 MRI 社区的广泛支持,从而促进更多的协调。同时允许在解决未解决的问题时进行改进和细化。该结果可能会得到肾脏 MRI 社区的广泛支持,从而促进更多的协调。
更新日期:2019-11-01
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