It is now well established that the exposure to certain environments such as farms has the potential to protect from the development of allergies later in life. This protection is achieved when repeated exposure to the farming environment occurs early in life, but persists when children spend sufficient amount of time in contact with livestock and hay, and drink unpasteurized milk. The capacity of farm dust to protect from allergy development lies, amongst others, in the microbe composition in the farm. These protective microbes release various metabolites and cell wall components that change farmers' home dust composition, when compared to urbanized home dust. Additionally, they can colonize various barrier sites (skin, lung, intestine) in farmers' children, leading to persistent changes in the way their immune system and their barrier cells respond to environmental allergens.

中文翻译：

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农业环境如何预防特应性疾病。

现已公认，暴露于某些环境（例如农场）有可能保护人们免受晚年过敏症的影响。早在生活中反复暴露于耕作环境就可以实现这种保护，但是当儿童花费足够的时间与牲畜和干草接触并喝未经巴氏消毒的牛奶时，这种保护就会持续。除其他因素外，农场扬尘防止过敏发展的能力还取决于农场中的微生物组成。与城市化的家庭灰尘相比，这些保护性微生物释放出各种代谢物和细胞壁成分，从而改变了农民的家庭灰尘组成。此外，它们可以在农民子女的各种屏障位点（皮肤，肺，肠）定殖，