The dietary inflammatory index (DII) is a novel way of describing diet that has been studied in relation to various health conditions, including cardiovascular disease (CVD) in several populations. We aimed to investigate the association between DII and CVD events among a representative population sample in northeastern Iran. This prospective cohort study was a subsample of 4,672 adults aged 35–65 years, and recruited as part of Mashhad stroke and heart atherosclerotic disorder cohort study population. The DII was computed at baseline according to a 65‐item validated food frequency questionnaire. Cox regression was used to determine the association of DII with incident CVD. One hundred twenty‐four participants developed CVD (including 24 cases of myocardial infarction [MI], 34 cases of stable angina [SA], and 66 cases of unstable angina [UA]). After adjusting for potential confounding factors, a hazard ratios of 1.06 (95% confidence interval: 0.70–1.60), 1.36 (95% confidence interval: 0.52–3.52), 1.33 (95% confidence interval: 0.60–2.94), and 0.86 (95% confidence interval: 0.48–1.53) were found for total CVD, MI, SA, and UA events, respectively, among the participants with proinflammatory diet (DII ≥ 0) versus those with anti‐inflammatory diet (DII < 0). There was no statistically significant association between the DII and total CVD, MI, SA, or UA in this population of middle‐aged Iranian men and women.

中文翻译：

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马什哈德卒中和心脏动脉粥样硬化研究人群中饮食炎症指数与心血管疾病风险之间的关联

饮食炎症指数 (DII) 是一种描述饮食的新方法，已针对多种健康状况进行了研究，包括多个人群的心血管疾病 (CVD)。我们旨在调查伊朗东北部代表性人群样本中 DII 与 CVD 事件之间的关联。这项前瞻性队列研究是 4,672 名 35-65 岁成年人的子样本，并作为马什哈德中风和心脏动脉粥样硬化队列研究人群的一部分招募。DII 是根据 65 项经验证的食物频率问卷在基线时计算的。Cox 回归用于确定 DII 与 CVD 事件的关联。124 名参与者发展为 CVD（包括 24 例心肌梗死 [MI]、34 例稳定型心绞痛 [SA] 和 66 例不稳定型心绞痛 [UA]）。调整潜在混杂因素后，风险比为 1.06（95% 置信区间：0.70-1.60）、1.36（95% 置信区间：0.52-3.52）、1.33（95% 置信区间：0.60-2.94）和 0.86（在促炎饮食（DII ≥ 0）与抗炎饮食（DII < 0）的参与者中，总 CVD、MI、SA 和 UA 事件的 95% 置信区间：0.48-1.53​​）。在伊朗中年男性和女性人群中，DII 与总 CVD、MI、SA 或 UA 之间没有统计学上的显着关联。促炎饮食（DII ≥ 0）与抗炎饮食（DII < 0）的参与者分别发生和 UA 事件。在伊朗中年男性和女性人群中，DII 与总 CVD、MI、SA 或 UA 之间没有统计学上的显着关联。促炎饮食（DII ≥ 0）与抗炎饮食（DII < 0）的参与者分别发生和 UA 事件。在伊朗中年男性和女性人群中，DII 与总 CVD、MI、SA 或 UA 之间没有统计学上的显着关联。