ABSTRACT The aim of the study was to investigate if dietary alpha-ketoglutarate (AKG) supplementation may improve the performance of lactating sows and their suckling piglets. After farrowing, 24 lactating sows (Large White × Landrace) with similar body weight (BW) were assigned to the control and AKG groups based on parity, and their lactation diets were supplemented with 0.00 or 0.25% AKG, respectively. It was found that supplementing the diet of lactating sows with 0.25% AKG enhanced growth performance of the suckling piglets from d 7 to d 21 of the lactation period, improved villus height of ileum and tended (p = 0.085) to increase mean volumetric bone mineral density of femur in the weanling piglets. In the lactating sows, dietary supplementation of AKG decreased plasma urea level on d 14 of lactation, decreased plasma calcium (Ca) concentrations from d 7 to d 21 of lactation and increased lactose and Ca levels in ordinary milk. Thus, it was proposed that AKG supplementation stimulates the capacity for lactose synthesis and Ca uptake in the mammary gland, thereby altering the composition of the ordinary milk which might be associated with the enhanced performance of piglets during the suckling period. These findings could lead to a better application of AKG in lactating nutrition, and therefore, promoting pork production.

中文翻译：

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母猪哺乳期补充α-酮戊二酸对哺乳母猪和哺乳仔猪生产性能的影响

摘要 本研究的目的是调查日粮中添加 α-酮戊二酸 (AKG) 是否可以改善泌乳母猪及其哺乳仔猪的生产性能。分娩后，根据胎次将24头体重（BW）相似的泌乳母猪（大白×长白）分为对照组和AKG组，分别在其泌乳日粮中添加0.00%或0.25%的AKG。结果表明，在泌乳母猪日粮中添加 0.25% AKG 可提高哺乳期第 7 天至第 21 天乳仔猪的生长性能，改善回肠绒毛高度并趋向于（p = 0.085）增加平均体积骨矿物质断奶仔猪股骨密度。在泌乳母猪中，日粮补充 AKG 降低了泌乳第 14 天的血浆尿素水平，从泌乳第 7 天到第 21 天，血浆钙 (Ca) 浓度降低，普通牛奶中的乳糖和钙水平升高。因此，有人提出补充 AKG 会刺激乳腺中乳糖合成和钙吸收的能力，从而改变普通牛奶的成分，这可能与仔猪在哺乳期的性能提高有关。这些发现可能导致 AKG 在泌乳营养中的更好应用，从而促进猪肉生产。从而改变普通牛奶的成分，这可能与哺乳期仔猪的性能提高有关。这些发现可能导致 AKG 在泌乳营养中的更好应用，从而促进猪肉生产。从而改变普通牛奶的成分，这可能与哺乳期仔猪的性能提高有关。这些发现可能导致 AKG 在泌乳营养中的更好应用，从而促进猪肉生产。