Hydrazones and their derivatives are very important compounds in medicinal chemistry due to their reported biological activity for the treatment of several diseases, like Alzheimer's, cancer, inflammation, and leishmaniasis. However, most of the investigations on hydrazones available in literature today are directed to the synthesis of these molecules with little discussion available on their biological activities. With the purpose of bringing lights into this issue, we performed a revision of the literature and wrote this review based on some of the most current research reports of hydrazones and derivatives, making it clear that the synthesis of these molecules can lead to new drug prototypes. Our goal is to encourage more studies focused on the synthesis and evaluation of new hydrazones, as a contribution to the development of potential new drugs for the treatment of various diseases.

中文翻译：

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Hy及其衍生物的合成及其生物活性：综述。

reported及其衍生物是药物化学中非常重要的化合物，因为它们据报道具有治疗多种疾病的生物活性，例如阿尔茨海默氏病，癌症，炎症和利什曼病。然而，当今文献中对的大多数研究都针对这些分子的合成，而对其生物学活性的讨论很少。为了弄清这一问题，我们对文献进行了修订，并根据azo和衍生物的最新研究报告撰写了这篇综述，明确指出这些分子的合成可以产生新的药物原型。我们的目标是鼓励开展更多有关新的合成和评估的研究，