This review addressed erectile dysfunction, regarding pathophysiology and therapeutic strategies. The line of treatment includes phosphodiesterase type-5 inhibitors and other types of therapy like topical and stem-cell transplant. Scientific literature was assessed to investigate the impact of nanotechnology on erectile dysfunction therapy. Various nanotechnology approaches were applied, like vesicular systems, lipid-based carriers, nanocrystals, dendrimers, liquid crystalline systems and nanoemulsions. Smart nano-systems can alter the landscape of the modern pharmaceutical industry by re- investigation of pharmaceutically suboptimal but biologically active entities for treatment of erectile dysfunction which were previously considered undeveloped.

中文翻译：

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勃起功能障碍的治疗策略，重点是纳米药物的最新方法。

这项审查解决勃起功能障碍，有关病理生理学和治疗策略。治疗范围包括5型磷酸二酯酶抑制剂和其他类型的疗法，例如局部和干细胞移植。评估了科学文献以调查纳米技术对勃起功能障碍治疗的影响。应用了各种纳米技术方法，如水泡系统，基于脂质的载体，纳米晶体，树枝状聚合物，液晶系统和纳米乳剂。智能纳米系统可以通过重新研究治疗勃起功能障碍的药学上次优但具有生物活性的实体来改变现代制药业的前景，而以前人们认为这种实体尚未开发出来。