Respiratory illnesses are prevalent around the world, and inhalation-based therapies provide an attractive, noninvasive means of directly delivering therapeutic agents to their site of action to improve treatment efficacy and limit adverse systemic side effects. Recent trends in medicine and nanoscience have prompted the development of inhalable nanomedicines to further enhance effectiveness, patient compliance, and quality of life for people suffering from lung cancer, chronic pulmonary diseases, and tuberculosis. Herein, we discuss recent advancements in the development of inhalable nanomaterial-based drug delivery systems and analyze several representative systems to illustrate their key design principles that can translate to improved therapeutic efficacy for prevalent respiratory diseases. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Respiratory Disease.

中文翻译：

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可吸入纳米药物可提高常见肺部疾病的治疗效果。

呼吸系统疾病在世界范围内普遍存在，基于吸入的疗法提供了一种有吸引力的、非侵入性的方法，可以将治疗剂直接输送到其作用部位，以提高治疗效果并限制不良的全身副作用。医学和纳米科学的最新趋势推动了可吸入纳米药物的发展，以进一步提高肺癌、慢性肺病和肺结核患者的疗效、患者依从性和生活质量。在这里，我们讨论了基于可吸入纳米材料的药物输送系统开发的最新进展，并分析了几个具有代表性的系统，以说明它们的关键设计原则，这些原则可以转化为改善流行呼吸系统疾病的治疗效果。本文分类如下：