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A Life's Journey Through Insect Metamorphosis.
Annual Review of Entomology ( IF 15.0 ) Pub Date : 2020-01-10 , DOI: 10.1146/annurev-ento-011019-025103
Lynn M Riddiford 1
Affiliation  

This autobiographical article describes the research career of Lynn M. Riddiford from its early beginnings in a summer program for high school students at Jackson Laboratory to the present "retirement" at the Friday Harbor Laboratories. The emphasis is on her forays into many areas of insect endocrinology, supported by her graduate students and postdoctoral associates. The main theme is the hormonal regulation of metamorphosis, especially the roles of juvenile hormone (JH). The article describes the work of her laboratory first in the elucidation of the endocrinology of the tobacco hornworm, Manduca sexta, and later in the molecular aspects of the regulation of cuticular and pigment proteins and of the ecdysone-induced transcription factor cascade during molting and metamorphosis. Later studies utilized Drosophila melanogaster to answer further questions about the actions of JH.

中文翻译:

通过昆虫变态的人生旅程。

这篇自传性文章描述了Lynn M. Riddiford的研究生涯,从其在杰克逊实验室为高中生开设的夏季计划的早期开始到现在在星期五港湾实验室的“退休”。重点是在研究生和博士后的支持下,她涉足昆虫内分泌学的许多领域。主题是变态的激素调节,尤其是少年激素(JH)的作用。这篇文章首先介绍了她实验室的工作,首先阐明了烟草天蛾的内分泌学,然后阐述了蜕皮和变态过程中表皮和色素蛋白的调控以及蜕皮激素诱导的转录因子级联的分子方面。 。
更新日期:2020-04-21
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