The sheet-like endoplasmic reticulum (ER) of eukaryotic cells has been found to be riddled with spiral dislocations, known as 'Terasaki ramps', in the vicinity of which the doubled bilayer membranes which make up ER sheets can be approximately modeled by helicoids. Here we analyze diffusion on a surface with locally helicoidal topological dislocations, and use the results to argue that the Terasaki ramps facilitate a highly efficient transport of water-soluble molecules both within the lumen of the endoplasmic reticulum, and in the adjacent cytoplasmic space.

中文翻译：

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寺崎螺旋坡道和细胞内扩散。

已发现真核细胞的片状内质网（ER）充满螺旋位错，称为“ Terasaki斜面”，在其附近，构成ER片的双层双层膜可以近似地由螺旋体建模。在这里，我们分析了具有局部螺旋形拓扑错位的表面上的扩散，并使用结果论证了Terasaki坡道促进了内质网腔内和邻近细胞质空间中水溶性分子的高效运输。