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Mammary stem cells, where art thou?
WIREs Mechanisms of Disease ( IF 4.6 ) Pub Date : 2019-07-19 , DOI: 10.1002/wdev.357
Pengfei Lu 1 , Tao Zhou 1 , Chongshen Xu 1 , Yunzhe Lu 1
Affiliation  

Tremendous progress has been made in the field of stem cell biology. This is in part due to the emergence of various vertebrate organs, including the mammary gland, as an amenable model system for adult stem cell studies and remarkable technical advances in single cell technology and modern genetic lineage tracing. In the current review, we summarize the recent progress in mammary gland stem cell biology at both the adult and embryonic stages. We discuss current challenges and controversies, and potentially new and exciting directions for future research.

中文翻译:

乳腺干细胞,您在哪里?

干细胞生物学领域已经取得了巨大的进步。这部分是由于包括乳腺在内的各种脊椎动物器官的出现,可以作为成人干细胞研究的理想模型系统,以及单细胞技术和现代遗传谱系追踪技术的显着技术进步。在当前的审查中,我们总结了成年和胚胎阶段乳腺干细胞生物学的最新进展。我们讨论了当前的挑战和争议,以及未来研究的潜在新的和令人兴奋的方向。
更新日期:2019-07-19
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