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Visual Function, Organization, and Development of the Mouse Superior Colliculus.
Annual Review of Vision Science ( IF 5.0 ) Pub Date : 2018-06-01 , DOI: 10.1146/annurev-vision-091517-034142
Jianhua Cang 1 , Elise Savier 1 , Jad Barchini 2 , Xiaorong Liu 1
Affiliation  

The superior colliculus (SC) is the most prominent visual center in mice. Studies over the past decade have greatly advanced our understanding of the function, organization, and development of the mouse SC, which has rapidly become a popular model in vision research. These studies have described the diverse and cell-type-specific visual response properties in the mouse SC, revealed their laminar and topographic organizations, and linked the mouse SC and downstream pathways with visually guided behaviors. Here, we summarize these findings, compare them with the rich literature of SC studies in other species, and highlight important gaps and exciting future directions. Given its clear importance in mouse vision and the available modern neuroscience tools, the mouse SC holds great promise for understanding the cellular, circuit, and developmental mechanisms that underlie visual processing, sensorimotor transformation, and, ultimately, behavior.

中文翻译:

小鼠上丘的视觉功能,组织和发育。

上丘(SC)是小鼠中最突出的视觉中心。过去十年的研究极大地增进了我们对鼠标SC的功能,组织和发展的理解,鼠标SC已迅速成为视觉研究中的流行模型。这些研究描述了小鼠SC中多种多样且特定于细胞类型的视觉反应特性,揭示了它们的层流和地形组织,并将小鼠SC和下游途径与视觉引导的行为联系在一起。在这里,我们总结这些发现,并将其与其他物种的SC研究的丰富文献进行比较,并强调重要的差距和令人振奋的未来方向。鉴于其在鼠标视觉中的重要性以及可用的现代神经科学工具,鼠标SC在理解细胞,电路,
更新日期:2019-11-01
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