While much attention has been focused on the force-generating mechanisms responsible for shaping developing embryos, less is known about the ways in which cells in animal tissues respond to mechanical stimuli. Forces will arise within a tissue as the result of processes such as local cell death, growth and division, but they can also be an indirect consequence of morphogenetic movements in neighbouring tissues or be imposed from the outside, for example, by gravity. If not dealt with, the accumulation of stress and the resulting tissue deformation can pose a threat to tissue integrity and structure. Here we follow the time-course of events by which cells and tissues return to their preferred state following a mechanical perturbation. In doing so, we discuss the spectrum of biological and physical mechanisms known to underlie mechanical homeostasis in animal tissues.

中文翻译：

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时间问题：组织对机械力的适应。

虽然很多注意力都集中在负责塑造发育中的胚胎的力产生机制上，但对动物组织中的细胞对机械刺激作出反应的方式知之甚少。作为局部细胞死亡、生长和分裂等过程的结果，力会在组织内产生，但它们也可能是邻近组织中形态发生运动的间接结果，或者是由外部施加的，例如重力。如果不加以处理，应力的积累和由此产生的组织变形会对组织的完整性和结构构成威胁。在这里，我们跟踪事件的时间过程，细胞和组织在机械扰动后返回到它们的首选状态。在这样做，