Innate lymphoid cells (ILC) are a specialized family of effector lymphocytes that transcriptionally and functionally mirror effector subsets of T cells, but differ from T cells in that they lack clonally distributed adaptive antigen receptors. Our understanding of this family of lymphocytes is still in its infancy. In this review, we summarize current understanding and discuss recent insights into the cellular and molecular events that occur during early ILC development in adult mice. We discuss how these events overlap and diverge with the early development of adaptive T cells, and how they may influence the molecular and functional properties of mature ILC.

中文翻译：

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成人先天性淋巴样细胞的发育。

先天性淋巴样细胞（ILC）是特化的效应子家族，在转录和功能上都反映了T细胞的效应子亚组，但与T细胞的不同之处在于它们缺乏克隆分布的适应性抗原受体。我们对该淋巴细胞家族的了解仍处于起步阶段。在这篇综述中，我们总结了当前的理解并讨论了对成年小鼠早期ILC发育过程中发生的细胞和分子事件的最新见解。我们讨论这些事件如何与自适应T细胞的早期发展重叠和分歧，以及它们如何影响成熟ILC的分子和功能特性。