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Gender difference in interactions between MAOA promoter uVNTR polymorphism and negative familial stressors on body mass index among Chinese adolescents.
Pediatric Obesity ( IF 2.7 ) Pub Date : 2013-06-13 , DOI: 10.1111/j.2047-6310.2013.00181.x B Xie 1 , D Li , S J London , P H Palmer , C A Johnshon , Y Li , J Shih , A W Bergen , D Nishita , G E Swan , R Ahn , D V Conti
Pediatric Obesity ( IF 2.7 ) Pub Date : 2013-06-13 , DOI: 10.1111/j.2047-6310.2013.00181.x B Xie 1 , D Li , S J London , P H Palmer , C A Johnshon , Y Li , J Shih , A W Bergen , D Nishita , G E Swan , R Ahn , D V Conti
Affiliation
Monoamine oxidase A (MAOA) modulates metabolism of serotonin and dopamine metabolism, neurotransmitters involved in regulation of appetite and food intake. The gene coding for MAOA contains a 30‐bp tandem repeat (uVNTR) polymorphism in its promoter region that has been previously identified to be associated with obesity with mixed findings in the literature. Our goals were to replicate the population effects of this functional polymorphism on obesity risk, and to further explore gender differences and interaction effects with negative stressors.
更新日期：2013-06-13
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