Maturation of long-running birth cohort studies has fostered a life course approach to adult health, function, and disease and related to conceptual frameworks. Using broad concepts of human development including physical, cognitive, and emotional function, birth cohorts provide insights into the processes across the life course and between generations that link to adult outcomes. We discuss findings on the determinants and health consequences of lifetime trajectories of body size, cognitive and emotional function, and socioeconomic position. Findings from the studies suggest that, for some adult health outcomes, explanations will be incomplete unless exposures and processes from across the life course are taken into account. New birth cohort studies are poised to delineate further the nature and timing of life course relationships in contemporary generations of children.

中文翻译：

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从成人疾病的发育起源到成人疾病和衰老的生命历程研究：来自出生队列研究的见解。

长期出生队列研究的成熟促进了成人健康、功能和疾病的生命历程方法，并与概念框架相关。使用包括身体、认知和情感功能在内的人类发展的广泛概念，出生队列提供了对整个生命历程以及与成人结果相关的几代人之间的过程的见解。我们讨论了关于身体大小、认知和情绪功能以及社会经济地位的终生轨迹的决定因素和健康后果的发现。研究结果表明，对于某些成人健康结果，除非考虑到整个生命过程中的暴露和过程，否则解释将是不完整的。