Sense organs and cranial sensory ganglia are functionally diverse, yet share a common developmental origin. They arise from a pool of multipotent progenitors and local signals gradually restrict their development potential to specify the inner ear, olfactory epithelium, lens and sensory neurons. This process requires the temporal integration of multiple signalling pathways, cross-repressive transcription factor interactions and tight coordination of cell fate specification and morphogenesis.

中文翻译：

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脊椎动物头部感觉神经系统的发育：准时的重要性。

感觉器官和颅感觉神经节功能多样，但有着共同的发育起源。它们来自多能祖细胞池，局部信号逐渐限制它们的发育潜力，以指定内耳、嗅觉上皮、晶状体和感觉神经元。这个过程需要多个信号通路的时间整合、交叉抑制转录因子相互作用以及细胞命运规范和形态发生的紧密协调。