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The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department.
Clinical Biochemistry ( IF 2.5 ) Pub Date : 2009-11-10 , DOI: 10.1016/j.clinbiochem.2009.11.004
Peter A Kavsak 1 , Alice M Newman , Dennis T Ko , Andrew R Macrae , Allan S Jaffe
Affiliation  

OBJECTIVE To determine if a cytokine panel could be informative regarding subsequent heart failure(HF)/death. DESIGN AND METHODS In 216 subjects presenting with chest pain to an emergency department in 1996, EDTA plasma (-70 degrees C) was thawed for IL-6, MCP-1, IL-10, VEGF, EGF measurement. RESULTS Subjects with any three cytokines elevated were at higher risk for HF/death compared to those with < or = two cytokines elevated. DISCUSSION A cytokine panel might be useful for risk stratification for HF/death.

中文翻译:

使用细胞因子面板来定义在急诊科就诊的胸痛患者心力衰竭/死亡的长期风险分层。

目的 确定细胞因子组是否可以提供有关后续心力衰竭 (HF)/死亡的信息。设计和方法 1996 年,在急诊科就诊的 216 名患有胸痛的受试者中,将 EDTA 血浆(-70 摄氏度)解冻用于 IL-6、MCP-1、IL-10、VEGF、EGF 测量。结果 与<或=两种细胞因子升高的受试者相比,任何三种细胞因子升高的受试者发生心衰/死亡的风险更高。讨论 细胞因子组可能有助于心衰/死亡的风险分层。
更新日期:2009-11-10
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