Five years ago, little was known about mechanisms of apoptotic execution. Now, one class of cell-death gene, the cysteine and aspartases (caspases) has come under intensive study. This review discusses the two classes of caspases, the reasons why humans may have so many caspase genes, the growing list of caspase substrates, and viral and pharmacological caspase inhibitors.

中文翻译：

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胱天蛋白酶和半胱天冬酶抑制剂。

五年前，人们对细胞凋亡执行机制知之甚少。现在，一类细胞死亡基因，半胱氨酸和天冬氨酸酶（胱天蛋白酶）已被深入研究。这篇综述讨论了两类半胱天冬酶，人类为何拥有如此众多的半胱天冬酶基因的原因，半胱天冬酶底物的清单在增加，以及病毒和药理学的半胱天冬酶抑制剂。