Suemoto et al. (6) reported differences in neuropathological lesions in the very old and younger individuals from a large Brazilian autopsy study as being possibly related to ethnic factors. In previous work the same authors demonstrated that African ancestry was inversely correlated with neuritic plaques, but not with neurofibrilary tangles, compared to Caucasian ancestry (5), suggesting also that unknown genetic variants or environmental factors associated with African ancestry reduce the accumulation of β-amyloid or increase its clearance.

中文翻译：

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人体测量学而非种族因素可以解释阿尔茨海默型神经退行性变化发生率的差异。

末本等人。(6) 根据一项大型巴西尸检研究报告了非常年长和年轻个体的神经病理学病变的差异，这可能与种族因素有关。在之前的工作中，同一作者证明，与高加索血统相比，非洲血统与神经炎斑块呈负相关，但与神经原纤维缠结无关 (5)，这也表明与非洲血统相关的未知遗传变异或环境因素会减少 β-淀粉样蛋白或增加其清除率。