Fibropapillomatosis is a panzootic and chronic disease among Chelonia mydas—usually associated with anthropogenic impacts. This study contributes towards understanding fibropapillomatosis implications for C. mydas populations as a reflector of environmental quality, via prevalence and histological, molecular and blood analyses at a World Heritage site in southern Brazil. Sixty-three juvenile C. mydas (31.3–54.5 cm curved carapace length–CCL) were sampled during two years. Eighteen specimens (~ 29%) had tumours (which were biopsied), while 45 had none. Degenerative changes in the epidermis and Chelonid alphaherpesvirus 5 DNA detection with three variants support a herpesvirus infection. Phylogenetic analysis indicated that variants A and B were similar to a herpesvirus lineage from the Atlantic group, but variant C was similar to a herpesvirus from the eastern Pacific lineage and represents the first published case for marine turtles off Brazil. Significantly lower levels of seven blood parameters, but greater numbers of eosinophils, were observed in tumour-afflicted animals. These observations were attributed to metabolism efficiencies and/or differences in diet associated with temporal-recruitment bias and disease development, and greater non-specific immune stimulation. While most animals had adequate body condition independent of disease, longer-term studies are required to elucidate any protracted population effects.

中文翻译：

---

受纤维支气管扩张症影响的Chelonia mydas中的Chelonid Alphaherpesvirus 5 DNA。

Fibropapillomatosis是当中的次流行和慢性疾病的绿海龟-通常与人为影响有关。这项研究有助于趋向于理解fibropapillomatosis影响C.海龟在巴西南部一个世界遗产作为人口环境质量的反射器，通过流行和组织学，分子和血液分析。六十三岁的my。c。mydas（两年中抽取了31.3–54.5 cm弯曲的甲壳长度– CCL）。18个标本（约29％）有肿瘤（经活检），而45个标本没有。表皮的退化性变化和具有三种变体的Chelonidα疱疹病毒5 DNA检测支持疱疹病毒感染。系统发育分析表明，变体A和B与大西洋沿岸的疱疹病毒谱系相似，但变异体C与从东太平洋沿岸谱系的疱疹病毒相似，代表了巴西海龟首次公开发表的病例。在患肿瘤的动物中观察到七个血液参数的水平明显降低，但嗜酸性粒细胞数量却增加。这些观察结果归因于新陈代谢效率和/或与时效偏差和疾病发展相关的饮食差异，以及更大的非特异性免疫刺激。尽管大多数动物的身体状况均与疾病无关，但需要进行长期研究才能阐明长期的种群影响。