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Phytochemical Analysis and Evaluation of Antimicrobial Activity of Peumus boldus, Psidium guajava, Vernonia polysphaera, Persea Americana, Eucalyptus citriodora Leaf Extracts and Jatropha multifida Raw Sap.
Current Pharmaceutical Biotechnology ( IF 2.8 ) Pub Date : 2019-04-10 , DOI: 10.2174/1389201020666190409104910 Jhonatas Emílio Ribeiro da Cruz 1 , Joyce Ferreira da Costa Guerra 1 , Marcos de Souza Gomes 2 , Guilherme Ramos Oliveira E Freitas 1 , Enyara Rezende Morais 1
Current Pharmaceutical Biotechnology ( IF 2.8 ) Pub Date : 2019-04-10 , DOI: 10.2174/1389201020666190409104910 Jhonatas Emílio Ribeiro da Cruz 1 , Joyce Ferreira da Costa Guerra 1 , Marcos de Souza Gomes 2 , Guilherme Ramos Oliveira E Freitas 1 , Enyara Rezende Morais 1
Affiliation
BACKGROUND
Currently, the treatment of infectious diseases has not always been successful due to the emergence of microbial resistance worldwide.
OBJECTIVES
This study aimed to evaluate the antioxidant activity, content of total phenolic compounds and flavonoids, antifungal potential and antibacterial action of six medicinal plants found in the Cerrado, leaf extracts of Boldo (Peumus boldus), Goiaba (Psidium guajava), Assa-Peixe (Vernonia polysphaera), Abacate (Persea americana), Eucalipto (Eucalyptus citriodora) and raw sap of Bálsamo (Jatropha multifida).
METHODS
The antioxidant activity was also determined through the DPPH, ABTS and phosphomolybdenum assays. In addition, the total phenolic content and flavonoid dosage were analyzed using the Folin- Ciocalteu method and the aluminum chloride test, respectively.
RESULTS
All extracts, except from Assa-Peixe, showed promising values against Staphylococcus aureus, with halos varying from 13-20 mm. Analysis of the minimum inhibitory concentration (MIC) values of the six medicinal plants revealed inhibitory activity of S. aureus, with concentrations varying from 3.12-12.5 mg/mL, which is a significant result considering that S. aureus is one of the main causes of hospital infections.
CONCLUSION
In the analysis of the phytochemical profile, Goiaba contained the best yield of phenolic compounds and total flavonoids, as well as higher antioxidant activity by DPPH and phosphomolybdenum, demonstrating that this species contains antioxidant components that can sequester free radicals under in vitro conditions. Therefore, the crude extracts investigated are promising and their antibacterial and antioxidant actions should be thoroughly studied.
中文翻译：
豌豆，番石榴，番红花，Persea Americana，柠檬桉叶提取物和麻风树原汁液的植物化学分析和抗菌活性评估。
背景技术当前，由于全世界范围内微生物耐药性的出现，传染病的治疗并不总是成功的。目的本研究旨在评估在塞拉多发现的六种药用植物的抗氧化活性，总酚类化合物和类黄酮的含量，抗真菌潜力和抗菌作用，Boldo（Peumus boldus）的叶提取物，Goiaba（Psidium guajava），Assa-Peixe （Vernonia polysphaera），算盘（Persea americana），Eucalipto（Eucalyptus citriodora）和Bálsamo（Jatropha multifida）的原汁。方法还通过DPPH，ABTS和磷钼测定法测定抗氧化活性。此外，分别使用Folin-Ciocalteu方法和氯化铝试验分析了总酚含量和类黄酮用量。结果所有提取物，除了来自阿萨-佩克斯（Assa-Peixe）的产品外，其对金黄色葡萄球菌显示出可观的价值，光环在13-20毫米之间。对六种药用植物的最低抑菌浓度（MIC）值进行分析后发现，金黄色葡萄球菌具有抑制活性，浓度范围为3.12-12.5 mg / mL，考虑到金黄色葡萄球菌是主要原因，这是一个重要结果。医院感染。结论在对植物化学特征的分析中，戈亚巴的酚类化合物和总类黄酮的收率最高，并且DPPH和磷钼的抗氧化活性更高，表明该物种包含的抗氧化成分可以在体外条件下隔离自由基。因此，
更新日期：2019-11-01
中文翻译：
豌豆，番石榴，番红花，Persea Americana，柠檬桉叶提取物和麻风树原汁液的植物化学分析和抗菌活性评估。
背景技术当前，由于全世界范围内微生物耐药性的出现，传染病的治疗并不总是成功的。目的本研究旨在评估在塞拉多发现的六种药用植物的抗氧化活性，总酚类化合物和类黄酮的含量，抗真菌潜力和抗菌作用，Boldo（Peumus boldus）的叶提取物，Goiaba（Psidium guajava），Assa-Peixe （Vernonia polysphaera），算盘（Persea americana），Eucalipto（Eucalyptus citriodora）和Bálsamo（Jatropha multifida）的原汁。方法还通过DPPH，ABTS和磷钼测定法测定抗氧化活性。此外，分别使用Folin-Ciocalteu方法和氯化铝试验分析了总酚含量和类黄酮用量。结果所有提取物，除了来自阿萨-佩克斯（Assa-Peixe）的产品外，其对金黄色葡萄球菌显示出可观的价值，光环在13-20毫米之间。对六种药用植物的最低抑菌浓度（MIC）值进行分析后发现，金黄色葡萄球菌具有抑制活性，浓度范围为3.12-12.5 mg / mL，考虑到金黄色葡萄球菌是主要原因，这是一个重要结果。医院感染。结论在对植物化学特征的分析中，戈亚巴的酚类化合物和总类黄酮的收率最高，并且DPPH和磷钼的抗氧化活性更高，表明该物种包含的抗氧化成分可以在体外条件下隔离自由基。因此，
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