Pharmacogenomics (PGx) is increasingly being recognized as a potential tool for improving the efficacy and safety of drug therapy. Therefore, several efforts have been undertaken globally to facilitate the implementation process of PGx into routine clinical practice. Part of these efforts include the formation of PGx working groups working on PGx research, synthesis, and dissemination of PGx data and creation of PGx implementation strategies. In Asia, the Southeast Asian Pharmacogenomics Research Network (SEAPharm) is established to enable and strengthen PGx research among the various PGx communities within but not limited to countries in SEA; with the ultimate goal to support PGx implementation in the region. From the perspective of SEAPharm member countries, there are several key elements essential for PGx implementation at the national level. They include pharmacovigilance database, PGx research, health economics research, dedicated laboratory to support PGx testing for both research and clinical use, structured PGx education, and supportive national health policy. The status of these essential elements is presented here to provide a broad picture of the readiness for PGx implementation among the SEAPharm member countries, and to strengthen the PGx research network and practice in this region.

中文翻译：

---

东南亚药物基因组学研究网络 (SEAPharm)：现状和前景

药物基因组学 (PGx) 越来越被认为是提高药物治疗疗效和安全性的潜在工具。因此，在全球范围内开展了多项努力，以促进 PGx 在常规临床实践中的实施过程。这些努力的一部分包括成立 PGx 工作组，致力于 PGx 研究、合成和传播 PGx 数据以及创建 PGx 实施策略。在亚洲，建立了东南亚药物基因组学研究网络 (SEAPharm)，以促进和加强东南亚国家内（但不限于）各个 PGx 社区之间的 PG​​x 研究；最终目标是支持该地区的 PGx 实施。从 SEAPharm 成员国的角度来看，有几个关键要素对于在国家层面实施 PGx 至关重要。它们包括药物警戒数据库、PGx 研究、卫生经济学研究、支持研究和临床使用 PGx 测试的专用实验室、结构化 PGx 教育和支持性国家卫生政策。此处介绍这些基本要素的状态是为了全面了解 SEAPharm 成员国实施 PGx 的准备情况，并加强该地区的 PGx 研究网络和实践。