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Review: Enhancing intramuscular fat development via targeting fibro-adipogenic progenitor cells in meat animals.
Animal ( IF 4.0 ) Pub Date : 2019-10-04 , DOI: 10.1017/s175173111900209x
X Li 1, 2 , X Fu 3 , G Yang 1 , M Du 2
Affiliation  

In the livestock industry, subcutaneous and visceral fat pads are considered as wastes, while intramuscular fat or marbling fat is essential for improving flavor and palatability of meat. Thus, strategies for optimizing fat deposition are needed. Intramuscular adipocytes provide sites for lipid deposition and marbling formation. In the present article, we addressed the origin and markers of intramuscular adipocyte progenitors - fibro-adipogenic progenitors (FAPs), as well as the latest progresses in mechanisms regulating the proliferation and differentiation of intramuscular FAPs. Finally, by targeting intramuscular FAPs, possible nutritional manipulations to improve marbling fat deposition are discussed. Despite recent progresses, the properties and regulation of intramuscular FAPs in livestock remain poorly understood and deserve further investigation.

中文翻译:

综述:通过靶向肉类动物的纤维致脂肪祖细胞来增强肌肉内脂肪的发育。

在畜牧业中,皮下和内脏脂肪垫被视为废物,而肌内脂肪或大理石花纹脂肪对于改善肉的风味和适口性至关重要。因此,需要优化脂肪沉积的策略。肌内脂肪细胞提供脂质沉积和大理石花纹形成的部位。在本文中,我们探讨了肌内脂肪细胞祖细胞-纤维化脂肪祖细胞(FAP)的起源和标记,以及调节肌内FAP增殖和分化的机制的最新进展。最后,通过针对肌内FAP,讨论了改善大理石花纹脂肪沉积的可能的营养操作。尽管有最新进展,
更新日期:2019-11-01
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