Polycystic Ovary Syndrome (PCOS) is a common endocrine and metabolic disorder that affects women in their reproductive age. Recent studies have shown that genes have an important role in the etiology of PCOS. However, the precise way in which these genes are transcriptionally and post-transcriptionally regulated is poorly understood.

The aim of the present review is to provide updated information on miRNAs and DNA methylation as epigenetic marks of PCOS.

The data presented here allow concluding that both microRNAs and DNA methylation can be considered as possible useful biomarkers when choosing the treatment for a specific PCOS phenotype and thus represent two important tools for the diagnosis and treatment of PCOS patients.

多囊卵巢综合症（PCOS）是一种常见的内分泌和代谢疾病，会影响育龄妇女。最近的研究表明，基因在PCOS的病因中具有重要作用。但是，人们对这些基因转录和转录后调控的确切方式知之甚少。

本审查的目的是提供有关miRNA和DNA甲基化作为PCOS的表观遗传标记的最新信息。

此处提供的数据可以得出结论，在选择特定PCOS表型的治疗方法时，可以将microRNA和DNA甲基化视为可能有用的生物标志物，因此代表了诊断和治疗PCOS患者的两个重要工具。