Identifying the neural correlates of positive interactions between friendship dyads may provide insights into mechanisms associated with adolescent social development. Forty-eight 14- to 18-year-old typically developing adolescents were video-recorded discussing a shared positive event with a close friend and subsequently viewed clips during an fMRI scan of that friend during the interaction and of an unfamiliar peer in a similar interaction. Adolescents also reported on their positive affect in daily life while with friends using ecological momentary assessment. We used multivariate repeated measures models to evaluate how positive affect with friends in the laboratory and in daily life was associated with neural response to friend and stranger positive and neutral clips. Adolescents who exhibited more positive affect when with friends in the laboratory showed less dorsolateral prefrontal cortex to friend positive clips. More positive affect when with friends in daily life was associated with less bilateral anterior insula response to friend positive clips, but greater left anterior insula response to stranger positive clips. Findings provide information on the role of lateral prefrontal cortex and anterior insula in enjoyment of friendships during adolescence.

中文翻译：

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亲密朋友之间的积极影响：青春期的大脑行为关联。

确定友谊二元组之间积极互动的神经相关性可能会提供对与青少年社会发展相关的机制的见解。48 名 14 至 18 岁的发育正常的青少年被录制视频，与一位密友讨论共同的积极事件，随后在互动过程中对该朋友的 fMRI 扫描以及在类似互动中对陌生同伴的 fMRI 扫描观看了片段. 青少年还报告了他们在日常生活中与朋友一起使用生态瞬时评估的积极影响。我们使用多变量重复测量模型来评估在实验室和日常生活中与朋友的积极影响如何与对朋友和陌生人积极和中性剪辑的神经反应相关联。在实验室与朋友相处时表现出更多积极影响的青少年显示较少的背外侧前额叶皮层对朋友积极的片段。在日常生活中与朋友在一起时，更积极的影响与双侧前脑岛对朋友积极片段的反应较少有关，但左前脑岛对陌生人积极片段的反应更大。研究结果提供了关于外侧前额叶皮层和前脑岛在青春期享受友谊中的作用的信息。