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Interpreting cell wall 'virulence factors' of Mycobacterium tuberculosis.
Trends in Microbiology ( IF 14.0 ) Pub Date : 2001-05-05 , DOI: 10.1016/s0966-842x(01)02018-2
C E Barry 1
Affiliation  

The complex structure of the cell wall of Mycobacterium tuberculosis clearly contributes to the outcome of the dialogue between this pathogen and its host. The effects of mutations in cell wall components are likely to be quite complex, as individual components of the wall could have indirect effects that extend well beyond the physical integrity of the wall itself. Affected processes include the surface exposure or secretion of the many lipid, glycolipid and proteinaceous molecules that can interact directly with components of the host cell.

中文翻译:

解释结核分枝杆菌的细胞壁“毒力因子”。

结核分枝杆菌细胞壁的复杂结构显然有助于这种病原体与其宿主之间对话的结果。细胞壁成分突变的影响可能非常复杂,因为壁的各个成分可能具有间接作用,其作用远超出了壁本身的物理完整性。受影响的过程包括可以直接与宿主细胞成分相互作用的许多脂质,糖脂和蛋白质分子的表面暴露或分泌。
更新日期:2019-11-01
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