Enteric viruses infect the mammalian gastrointestinal tract which is home to a diverse community of intestinal bacteria. Accumulating evidence suggests that certain enteric viruses utilize these bacteria to promote infection. While this is not surprising considering their proximity, multiple viruses from different viral families have been shown to bind directly to bacteria or bacterial components to aid in viral replication, pathogenesis, and transmission. These data suggest that the concept of a single virus infecting a single cell, independent of the environment, needs to be reevaluated. In this review, I will discuss the current knowledge of enteric virus-bacterial interactions and discuss the implications for viral pathogenesis and transmission.

肠病毒感染哺乳动物的胃肠道，那里是多种肠道细菌群落的所在地。越来越多的证据表明某些肠病毒利用这些细菌促进感染。尽管考虑到它们的接近性并不奇怪，但已显示来自不同病毒家族的多种病毒可直接结合细菌或细菌成分，从而有助于病毒复制，发病机制和传播。这些数据表明，与环境无关的感染单个细胞的单个病毒的概念需要重新评估。在这篇综述中，我将讨论肠道病毒与细菌相互作用的最新知识，并讨论其对病毒发病机理和传播的影响。