BACKGROUND AND PURPOSE Ethnic disparities in stroke are well described, with a higher incidence of disability and increased mortality in Blacks versus Whites. We sought to compare the clinical outcomes between those ethnic groups after stroke endovascular therapy (ET). METHODS We performed a retrospective review of the prospectively acquired Grady Endovascular Stroke Outcomes Registry between September 1, 2010 and September 30, 2015. Patients were dichotomized into two groups - Caucasians and African-Americans - and matched for age, pretreatment glucose level, and baseline National Institutes of Health Stroke Scale (NIHSS) score. Baseline characteristics as well as procedural and outcome parameters were compared. RESULTS Out of the 830 patients treated with ET, 308 pairs of patients (n = 616) underwent primary analysis. African-Americans were younger (p < 0.01), had a higher prevalence of hypertension (p < 0.01) and diabetes (p = 0.04), and had higher Alberta Stroke Program Early CT Score values (p = 0.03) and shorter times to treatment (p = 0.01). Blacks more frequently had Medicaid coverage and less private insurance (29.6 vs. 11.4% and 41.5 vs. 60.3%, respectively, p < 0.01). The remaining baseline characteristics, including baseline NIHSS score and CT perfusion-derived ischemic core volumes, were well balanced. There were no differences in the overall distribution of 90-day modified Rankin scale scores (p = 0.28), rates of successful reperfusion (84.7 vs. 85.7%, p = 0.91), good outcomes (49.1 vs. 44%, p = 0.24), or parenchymal hematomas (6.5 vs. 6.8%, p = 1.00). Blacks had lower 90-day mortality rates (18 vs. 24.6%, p = 0.04) in univariate analysis, which persisted as a nonsignificant trend after adjustment for potential confounders (OR 0.52, 95% CI 0.26-1.03, p = 0.06). CONCLUSIONS Despite unique baseline characteristics, African-Americans treated with ET for large vessel occlusion strokes have similar outcomes as Caucasians. Greater availability of ET may diminish the ethnic/racial disparities in stroke outcomes.

中文翻译：

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血管内治疗和中风结果的种族差异。

背景和目的 中风的种族差异已得到充分描述，与白人相比，黑人的残疾发生率更高，死亡率也更高。我们试图比较这些种族群体在卒中血管内治疗（ET）后的临床结果。方法 我们对 2010 年 9 月 1 日至 2015 年 9 月 30 日期间前瞻性获得的 Grady 血管内卒中结果登记库进行了回顾性审查。患者被分为两组 - 白种人和非裔美国人 - 并匹配年龄、治疗前血糖水平和基线美国国立卫生研究院卒中量表 (NIHSS) 评分。比较基线特征以及程序和结果参数。结果 在接受 ET 治疗的 830 名患者中，有 308 对患者（n = 616）接受了初步分析。非裔美国人更年轻 (p < 0.01)，高血压 (p < 0.01) 和糖尿病 (p = 0.04) 患病率较高，艾伯塔省中风计划早期 CT 评分较高 (p = 0.03) 且治疗时间较短（p = 0.01）。黑人更多地拥有医疗补助，但较少拥有私人保险（分别为 29.6% vs. 11.4% 和 41.5% vs. 60.3%，p < 0.01）。其余基线特征，包括基线 NIHSS 评分和 CT 灌注衍生的缺血核心体积，得到了很好的平衡。90天改良Rankin量表评分（p = 0.28）、再灌注成功率（84.7 vs. 85.7%，p = 0.91）、良好结局（49.1 vs. 44%，p = 0.24）的总体分布没有差异。 ），或实质血肿（6.5 vs. 6.8%，p = 1.00）。在单变量分析中，黑人的 90 天死亡率较低（18% vs. 24.6%，p = 0.04），在调整潜在混杂因素后，这种趋势仍然不显着（OR 0.52，95% CI 0.26-1.03，p = 0.06）。结论 尽管基线特征独特，但接受 ET 治疗大血管闭塞性中风的非裔美国人与白人有相似的结果。提高 ET 的可用性可能会减少卒中结果中的民族/种族差异。