BACKGROUND The treatment of stroke is dependent on a narrow therapeutic time window that requires interventions to be emergently pursued. Despite recent "FAST" initiatives that have underscored "time is brain," many patients still fail to present within the narrow time window to receive maximum treatment benefit from advanced stroke therapies, including recombinant tissue plasminogen activator (tPA) and mechanical thrombectomy. The convergence of emergency medical services, telemedicine, and mobile technology, including transportable computed tomography scanners, has presented a unique opportunity to advance patient stroke care in the prehospital field by shortening time to hyperacute stroke treatment with a mobile stroke unit (MSU). SUMMARY In this review, we provide a look at the evolution of the MSU into its current status as well as future directions. Our summary statement includes historical and implementation information, economic cost, and published clinical outcome and time metrics, including the utilization rate of thrombolysis. KEY MESSAGES Initially hypothesized in 2003, the first MSUs were launched in Germany and adopted worldwide in acute, prehospital stroke management. These specialized ambulances have made the diagnosis and treatment of many neurological emergencies, in addition to ischemic and hemorrhagic stroke, possible at the emergency site. Providing treatment as early as possible, including within the prehospital phase of stroke management, improves patient outcomes. As MSUs continue to collect data and improve their methods, shortened time metrics are expected, resulting in more patients who will benefit from faster treatment of their acute neurological emergencies in the prehospital field.

中文翻译：

---

全球移动卒中组经验回顾。

背景技术中风的治疗依赖于狭窄的治疗时间窗，需要紧急采取干预措施。尽管最近的“FAST”倡议强调了“时间就是大脑”，但许多患者仍然未能在狭窄的时间窗口内就诊，从而无法从包括重组组织纤溶酶原激活剂 (tPA) 和机械血栓切除术在内的先进中风疗法中获得最大的治疗益处。紧急医疗服务、远程医疗和移动技术（包括便携式计算机断层扫描仪）的融合，为通过移动卒中单元 (MSU) 缩短超急性卒中治疗的时间来推进院前患者卒中护理提供了独特的机会。总结 在本次审查中，我们提供了 MSU 的演变到其当前状态以及未来方向的看法。我们的摘要声明包括历史和实施信息、经济成本以及公布的临床结果和时间指标，包括溶栓的利用率。关键信息 最初假设于 2003 年，第一批 MSU 在德国推出，并在全球范围内用于急性院前卒中管理。这些专业救护车使许多神经系统急症的诊断和治疗成为可能，除了缺血性和出血性中风外，在急救现场也成为可能。尽早提供治疗，包括在卒中管理的院前阶段，可以改善患者的预后。随着 MSU 继续收集数据并改进他们的方法，预计时间指标会缩短，