The introduction of optoelectrokinetics (OEK) into lab-on-a-chip systems has facilitated a new cutting-edge technique-the OEK-based micro/nanoscale manipulation, separation, and assembly processes-for the microfluidics community. This technique offers a variety of extraordinary advantages such as programmability, flexibility, high biocompatibility, low-cost mass production, ultralow optical power requirement, reconfigurability, rapidness, and ease of integration with other microfluidic units. This paper reviews the physical mechanisms that govern the manipulation of micro/nano-objects in microfluidic environments as well as applications related to OEK-based micro/nanoscale manipulation-applications that span from single-cell manipulation to single-molecular behavior determination. This paper wraps up with a discussion of the current challenges and future prospects for the OEK-based microfluidics technique. The conclusion is that this technique will allow more opportunities for biomedical and bioengineering researchers to improve lab-on-a-chip technologies and will have far-reaching implications for biorelated researches and applications in the future.

中文翻译：

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基于光电动力学的生物应用微流控平台：最新进展回顾。

将光电动学 (OEK) 引入芯片实验室系统，为微流体领域带来了一种新的尖端技术——基于 OEK 的微/纳米级操纵、分离和组装工艺。该技术具有多种非凡的优势，例如可编程性、灵活性、高生物相容性、低成本大规模生产、超低光功率要求、可重构性、快速性以及易于与其他微流体单元集成。本文回顾了控制微流体环境中微/纳米物体操纵的物理机制，以及与基于 OEK 的微/纳米尺度操纵相关的应用——从单细胞操纵到单分子行为测定。本文最后讨论了基于 OEK 的微流体技术当前的挑战和未来的前景。结论是，该技术将为生物医学和生物工程研究人员提供更多改进芯片实验室技术的机会，并对未来生物相关的研究和应用产生深远的影响。