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The association between detected drug resistance mutations and CD4+ T-cell decline in HIV-positive individuals maintained on a failing treatment regimen.
Antiviral Therapy ( IF 1.3 ) Pub Date : 2017-6-20 , DOI: 10.3851/imp3178
Anna Schultze 1 , Roger Paredes 2 , Caroline Sabin 1 , Andrew N Phillips 1 , Deenan Pillay 3, 4 , Nicola Mackie 5 , Antonella Castagna 6 , David Chadwick 7 , Karolin Falconer 8 , Anna Maria Geretti 9 , Frank A Post 10 , Teresa Hill 1 , Ole Kirk 11 , Anton Pozniak 12 , Mark Nelson 12 , Anna Tostevin 1 , David Dunn 1, 13 , Jens Lundgren 11 , Alessandro Cozzi-Lepri 1
Affiliation  

To analyse the effect of drug resistance mutations (DRM) on CD4+ T-cell (CD4) trends in HIV-positive people maintained on virologically failing antiretroviral therapy (ART).

中文翻译:

在失败的治疗方案中维持的 HIV 阳性个体中检测到的耐药性突变与 CD4+ T 细胞下降之间的关联。

分析耐药性突变 (DRM)对病毒学失败的抗逆转录病毒治疗 (ART) 的 HIV 阳性人群中CD4 + T 细胞 (CD4) 趋势的影响。
更新日期:2020-08-21
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