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Odontomas in Frogs.
Veterinary Pathology ( IF 2.3 ) Pub Date : 2019-09-24 , DOI: 10.1177/0300985819877633
Elise E B LaDouceur 1 , Amanda M Hauck 1 , Michael M Garner 2 , Andrew N Cartoceti 3 , Brian G Murphy 4
Affiliation  

Odontomas are variably differentiated, hamartoma-like proliferations of odontogenic epithelium, pulp ectomesenchyme (odontoblasts), and dental matrix. Frogs are polyphyodont and homodont. Their teeth also differ from mammals in that they are restricted to the upper jaw in adults and lack a periodontal ligament and cementum, attaching directly to the underlying bone. Odontomas were identified in an African clawed frog (Xenopus laevis), a false tomato frog (Dyscophus guineti), and a tomato frog of unknown species (Dyscophus sp.). All of the examined odontomas were composed of numerous tooth-like structures comprising an arc of dentinal matrix lined on the convex surface by ameloblasts and on the concave surface by odontoblasts. Masson's trichrome and immunohistochemistry with pan-cytokeratin supported these findings. The pathogenesis of these lesions may be displacement of the dental lamina, which has been shown in research studies to lead to de novo proliferation of dental elements in frogs.

中文翻译:

青蛙中的牙牙病。

牙牙瘤的分化程度不同,是牙源性上皮,牙髓外基质(成牙本质细胞)和牙基质的错构瘤样增生。青蛙是多phydoodont和homodont。它们的牙齿与哺乳动物的牙齿也不同,它们的牙齿仅限于成年人的上颚,并且缺少牙周膜和牙骨质,直接附着在下面的骨骼上。在非洲爪蛙(Xenopus laevis),假番茄蛙(Dyscophus guineti)和未知物种的番茄蛙(Dyscophus sp。)中发现了Ototomas。所有检查的牙本质由许多齿状结构组成,包括成牙细胞在凸表面上和牙本质成膜在凹表面上排列的牙质基质弧。Masson的三色和全细胞角蛋白的免疫组织化学支持了这些发现。
更新日期:2019-11-01
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