Myrcludex B is a first-in-class virus entry inhibitor for patients with chronic hepatitis B or B/D infections. In patients it will be coadministered with drugs needed for the disease or comorbidities. We aimed to define the risk of drug-drug interactions by characterizing the influence of myrcludex B on relevant drug transporting and metabolizing enzymes in vitro.

中文翻译：

---

HBV和HDV进入抑制剂Myrcludex B的药物-药物相互作用潜力在体外进行了评估。

Myrcludex B是用于慢性乙型肝炎或B / D感染患者的一流病毒进入抑制剂。在患者中，它将与疾病或合并症所需的药物合用。我们旨在通过表征Myrcludex B对体外相关药物运输和代谢酶的影响来定义药物相互作用的风险。