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Physiological correlates of calcium-accumulating properties of mitochondria: fish-muscle mitochondria.
Journal of Bioenergetics and Biomembranes ( IF 2.9 ) Pub Date : 1977-12-01 , DOI: 10.1007/bf00743149
H R Sulochana 1 , I Bashyam , S Narayan , J Jayaraman
Affiliation  

The mitochondria isolated from the muscles of fish acclimated to grow in different salinities have been studied with reference to their Ca2+ uptake capacity and compared to those isolated from fresh-water fish muscle. The results show a drastic response by the mitochondria with reference to their Ca2+ uptake function soon after exposure to the stress. Evidence is also presented to suggest an alteration in conformation. This perturbation appears to be the initial response to the stress since the normal state (as that of the fresh-water fish) is restored in course of time. Further, so far there is no indication that the electron transport function and ATP production are affected by the ionic stress conditions. This would support the physiological relevance of the mitochondrial capacity for Ca2+ uptake.

中文翻译:

线粒体钙积累特性的生理相关性:鱼肌肉线粒体。

从适应在不同盐度下生长的鱼的肌肉中分离出的线粒体已经参照它们的 Ca2+ 吸收能力进行了研究,并与从淡水鱼肌肉中分离出的线粒体进行了比较。结果显示线粒体在暴露于压力后不久就其 Ca2+ 吸收功能产生剧烈反应。还提供了证据表明构象发生了改变。这种扰动似乎是对压力的初始反应,因为正常状态(如淡水鱼的状态)会随着时间的推移而恢复。此外,到目前为止,还没有迹象表明电子传输功能和 ATP 产生受离子应力条件的影响。这将支持线粒体能力对 Ca2+ 吸收的生理相关性。
更新日期:2019-11-01
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