Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver. Hepatectomy and liver transplantation (LT) are regarded as the radical treatment, but great majority of patients are already in advanced stage on the first diagnosis and lose the surgery opportunity. Multifarious image-guided interventional therapies, termed as locoregional ablations, are recommended by various HCC guidelines for the clinical practice. Transarterial chemoembolization (TACE) is firstly recommended for intermediate-stage (Barcelona Clinic Liver Cancer (BCLC) B class) HCC but has lower necrosis rates. Radiofrequency ablation (RFA) is effective in treating HCCs smaller than 3 cm in size. Microwave ablation (MWA) can ablate larger tumor within a shorter time. Combination of TACE with RFA or MWA is effective and promising in treating larger HCC lesions but needs more clinical data to confirm its long-term outcome. The combination of TACE and RFA or MWA against hepatocellular carcinoma needs more clinical data for a better strategy. The characters and advantages of TACE, RFA, MWA, and TACE combined with RFA or MWA are reviewed to provide physician a better background on decision.

中文翻译：

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经肝动脉化疗栓塞与射频消融或微波消融联合治疗肝细胞癌的策略。

肝细胞癌（HCC）是最常见的肝原发癌。肝切除和肝移植（LT）被认为是根治性治疗，但是绝大多数患者在初诊时已经处于晚期，并且失去了手术机会。各种HCC指南针对临床实践推荐了多种影像引导介入治疗方法，称为局部区域消融术。首先建议在中期（巴塞罗那临床肝癌（BCLC）B级）肝癌中采用经动脉化学栓塞术（TACE），但其坏死率较低。射频消融（RFA）可有效治疗3 cm以下的HCC。微波消融（MWA）可以在更短的时间内消融更大的肿瘤。TACE与RFA或MWA的结合在治疗较大的HCC病变方面是有效且有前途的，但需要更多临床数据来确认其长期结果。TACE与RFA或MWA联合治疗肝细胞癌需要更多的临床数据，以寻求更好的策略。回顾了TACE，RFA，MWA和TACE与RFA或MWA相结合的特点和优势，以为医生提供更好的决策依据。