Introduction Elastin-like polypeptide (ELP) supplementation was previously reported to enhance the physical properties of mineral trioxide aggregate (MTA). The aim of this study was to investigate the effect of ELP supplementation on the bonding properties of MTA to dentin. Methods Two types of ELPs were synthesized and mixed with MTA in a 0.3 liquid/powder ratio. The push-out bond strength test and interfacial observation with scanning electron microscopy were performed for ELP-supplemented MTA. The porosity of MTA fillings in the cavity was observed with microcomputed tomography. The stickiness, flow rate, and contact angle were additionally measured for potential increased bonding properties. Results ELP supplementation improved the bond strength of MTA to dentin. MTA supplemented by a specific ELP exhibited a less porous structure, higher stickiness, and higher flow rate. ELPs also decreased the contact angle to dentin. Conclusions This research data verifies that ELP improves the bonding properties of MTA to a tooth structure. The sticky and highly flowable characteristics of ELP-supplemented MTA may provide intimate contact with dentin and supply a less porous cement structure, which might improve the bonding properties of MTA.

中文翻译：

---

弹性蛋白样多肽补充剂改善矿物三氧化物聚集体的粘合性能

前言 弹性蛋白样多肽 (ELP) 补充剂曾被报道可增强矿物三氧化物聚集体 (MTA) 的物理特性。本研究的目的是研究 ELP 补充剂对 MTA 与牙本质的粘合特性的影响。方法合成两种ELPs并与MTA以0.3的液/粉比混合。对添加 ELP 的 MTA 进行了推出粘合强度测试和扫描电子显微镜界面观察。用微型计算机断层扫描观察了腔内 MTA 填充物的孔隙率。另外还测量了粘性、流速和接触角，以了解潜在的增加的粘合性能。结果 ELP 补充剂提高了 MTA 与牙本质的结合强度。由特定 ELP 补充的 MTA 表现出较少孔的结构，更高的粘性和更高的流速。ELPs 还降低了与牙本质的接触角。结论 本研究数据证实 ELP 可改善 MTA 与牙齿结构的粘合性能。补充 ELP 的 MTA 的粘性和高度流动特性可以提供与牙本质的紧密接触并提供较少孔的水泥结构，这可能会改善 MTA 的粘合性能。