Curcumin (diferuloylmethane) derived from the rhizome of Curcuma longa L. has been used for thousands of years in traditional Chinese medicine and Ayurvedic medicine in Asian countries to treat liver diseases, rheumatoid diseases, diabetes, atherosclerosis, infectious diseases and cancer. It exhibits a wide range of pharmacological properties, which include antioxidant, anti-inflammatory, antimutagenic, antimicrobial and anticancer activity. Herein the mechanisms of curcumin impact on oxidative stress, angiogenesis and inflammatory processes are described indicating that curcumin use may inhibit those pathological conditions and restore body homeostasis. Its effectiveness was also proved for major eye diseases. In this review, the influence of curcumin on eye diseases, such as glaucoma, cataract, age-related macular degeneration, diabetic retinopathy, corneal neovascularization, corneal wound healing, dry eye disease, conjunctivitis, pterygium, anterior uveitis are reported. The analysis of a number of clinical and preclinical investigations indicates that curcumin may be used as a therapeutic agent in the treatment of various eye disorders.

中文翻译：

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姜黄素在眼部疾病中的治疗潜力。

源自姜黄根茎的姜黄素（二氟甲酰甲烷）在亚洲国家的传统中医药和印度草药疗法中已有数千年的历史，用于治疗肝脏疾病，类风湿性疾病，糖尿病，动脉粥样硬化，传染病和癌症。它具有广泛的药理特性，包括抗氧化剂，抗炎，抗诱变，抗微生物和抗癌活性。本文描述了姜黄素影响氧化应激，血管生成和炎症过程的机制，表明姜黄素的使用可以抑制那些病理状况并恢复体内稳态。还证明了其对主要眼病的有效性。在这篇评论中，姜黄素对眼睛疾病的影响，例如青光眼，白内障，与年龄有关的黄斑变性，据报道有糖尿病性视网膜病变，角膜新生血管，角膜伤口愈合，干眼症，结膜炎，翼状，肉，前葡萄膜炎。对许多临床和临床前研究的分析表明，姜黄素可以用作治疗各种眼疾的治疗剂。